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Literature summary extracted from

  • Medicus, R.G.; Melamed, J.; Arnaout, M.A.
    Role of human factor I and C3b receptor in the cleavage of surface-bound C3bi molecules (1983), Eur. J. Immunol., 13, 465-470.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.21.45 C3b receptor obligate cofactor for factor I-mediated cleavage of cell bound C3bi Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.45 K-76COOH
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.45 complement component C3bi + H2O Homo sapiens the breakdown of human erythrocyte-bound C3bi molecules in serum or plasma is mediated only by factor I ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.45 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.45 complement component C3bi + H2O complement component C3bi bound to human erythrocytes is rapidly cleaved, unlike complement component C3bi bound to other species Homo sapiens complement component C3c + ?
-
 ?
3.4.21.45 complement component C3bi + H2O the breakdown of human erythrocyte-bound C3bi molecules in serum or plasma is mediated only by factor I Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.45 C3b/C4b inactivator
-
 Homo sapiens